Paul Hanson named March 2023 Sutton Family Research Impact Award recipient

The Department of Chemistry congratulates Professor Paul Hanson on receiving the March 2023 Sutton Family Research Impact Award! His winning paper was published in the Journal of Organic Chemistry and is titled, “Total Synthesis of Sanctolide A and Formal Synthesis of (2S)-Sanctolide A.”

The Department of Chemistry congratulates Professor Paul Hanson on receiving the March 2023 Sutton Family Research Impact Award!

The Sutton Award is a monthly competition among chemistry faculty. Every month, the Chemistry Department Chair and Associate Chairs review the peer-reviewed papers published by chemistry faculty from the three previous months to select a winner. The recipient receives a $500 cash prize and is featured on the departmental website.

For a full list of winners, visit out Sutton Family Research Impact Award webpage.

https://pubs.acs.org/doi/10.1021/acs.joc.2c01922

Total Synthesis of Sanctolide A and Formal Synthesis of (2S)-Sanctolide A

Sanctolide A is a 14-membered macrocycle [technically a cyclic enamide/amide-containing] that belongs to a small subclass of marine natural products that are isolated from cyanobacteria [blue-green algae, Oscillatoria sancta (SAG 74.79)]. The unusual limited stability of Sanctolide A has inspired the development of synthetic pathways, which can enable access to analogs that are more stable and potentially more medicinally relevant for use in early phase drug discovery efforts.